Effects of Ethanol Leaf-Extract of Pterocarpus santalinoides on Haematological Parameters in Rats

Effects of ethanol leaf-extract of Pterocarpus santalinoides on haematological parameters were investigated in rats using spectrophotometric and centrifugation methods. Sixteen Wister albino rats were grouped into four (A, B, C and D). Groups A, B, C and D were administered the extract through oral intubation at the doses (mg/kg body weights) of 0, 200, 400 and 600 respectively for two weeks. The blood samples were collected on the fifteen day following the last day of administration. The Haemoglobin (Hb) levels (g/dl) recorded 12.30±0.69, 14.17±1.25, 15.63±1.19 and 15.07±0.93 for the animals in groups A, B, C and D respectively with corresponding levels (%) of packed cell volume (PCV) as 35.67±2.08, 43.00±1.61, 43.3±1.53 and 45.00±1.65. Platelet (PLT) levels (x10 /l) recorded 211.60±5.09, 347.67±3.91, 364.6±5.15 and 435±5.86 for groups A, B, C and 9 D respectively. Hence, the results showed significant (p<0.05) increase in the levels of haemoglobin, packed cell volume and platelets.